High, Lowboy!
Uninterrupted change of timbre certainly reproduces the effect of the speaker of the human voice, and not only by wah-wah. It is true that the harp is most suitable for this purpose; where you can even hear the words. In search of an example for sound of melodica, I stopped at American saxophonist Archie Shepp, who enjoys chewing movements of the mouth, thus edging closer the sound to the spoken. Unfortunately , on melodica sound modulation is small, probably also because of shape and size of mouthpiece (tap-hole) .